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Differences between G2 and G3 was not significant

Investigation of the potential mechanism of Alpinia officinarum Hance in improving type 2 diabetes mellitus based on network pharmacology and molecular docking

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The key findings from this clinical program include significant reductions in body weight and fat mass in treatment groups compared to placebo, preferential loss of abdominal and visceral adipose tissue, no changes in serum IGF-1 levels at any dose tested, no negative effects on glucose metabolism or insulin sensitivity, no significant adverse events related to metabolic or endocrine disruption, and safety profile indistinguishable from placebo for most parameters